hepatic fibrosis

The lab's research focuses on the mechanism of hepatic fibrosis.Liver fibrosis results from the deposition of excess, abnormal extracellular matrix by myofibroblasts derived from non-fibrogenic cells that undergo “activation” in the context of chron…

 

Biliary atresia

Human model diseases of interest to our studies of the mechanism of fibrosis include biliary atresia. We are part of an international group that has recently identified a plant toxin that causes biliary atresia. We have developed model mammalian cel…

 

Non-alcoholic fatty liver disease